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Mouse PCSK9

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  • ¥1200 - 17600
  • SinoBio
  • 国产
  • CA86
  • 2025年10月28日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Gln35-Gln155&Ser156-Gln694

    • 保质期

      See instructions

    • 英文名

      标签:C-6His

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥1200.0
    规格:50ug产品价格:¥3520.0
    规格:500ug产品价格:¥12320.0
    规格:1mg产品价格:¥17600.0
    产品描述
    Recombinant Mouse Proprotein Convertase Subtilisin/Kexin Type 9 is produced by our Mammalian expression system and the target gene encoding Gln35-Gln155&Ser156-Gln694 is expressed with a 6His tag at the C-terminus.
    蛋白编号
    Q80W65
    产品别称
    Proprotein Convertase Subtilisin/Kexin Type 9; Neural Apoptosis-Regulated Convertase 1; NARC-1; Proprotein Convertase 9; PC9; Subtilisin/Kexin-Like Protease PC9; Pcsk9; Narc1
    偶联
    Unconjugated
    分子量
    14&58.2 KDa
    表观分子量
    19&60 KDa, reducing conditions
    剂型描述
    Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 20% Glycerol, pH 7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    生物活性-ELISA
    Immobilized Recombinant Mouse PCSK9-His(Cat#CA86) at 2μg/ml (100 μl/well) can bind Biotinylated Human LDL R-His-Avi(Cat#CC70). The ED50 of Biotinylated Human LDL R-His-Avi(Cat#CC70) is 0.301 ug/ml. (Regularly tested)
    生物活性-BLI
    Loaded Biotinylated Human LDL R-Avi-His(Cat#CC70) on SA Biosensor, can bind Mouse PCSK9-His(Cat#CA86) with an affinity constant of 4.97 nM as determined in BLI assay. (Regularly tested)  
    运输条件
    • The product is shipped on dry ice/polar packs.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Store at ≤-70°C, stable for 6 months after receipt.
    • Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
    • Please minimize freeze-thaw cycles.
    产品背景
    Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis.PCSK9 also plays a role in neural development.

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    图标文献和实验
    该产品被引用文献

    Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis.PCSK9 also plays a role in neural development.

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    文献支持
    Mouse PCSK9
    ¥1200 - 17600