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Human GIPR (VLP, Full Length)

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  • ¥840 - 17600
  • SinoBio
  • 国产
  • C41R
  • 2026年04月27日
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    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Arg22-Arg421(Thr345Phe)

    • 保质期

      See instructions

    • 英文名

      标签:C-Flag

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥840.0
    规格:50ug产品价格:¥2520.0
    规格:500ug产品价格:¥12320.0
    规格:1mg产品价格:¥17600.0
    产品描述
    Recombinant Human Gastric inhibitory polypeptide receptor is produced by our Mammalian expression system and the target gene encoding Arg22-Arg421(Thr345Phe) is expressed with a Flag tag at C-terminus. A mutation (Thr345Phe) is introduced to stabilize the Human GIPR protein. VLPs are self-assembled from viral envelope/capsid protein and can display conformationally intact membrane protein in natural cell membranes.
    蛋白编号
    P48546
    产品别称
    Gastric inhibitory polypeptide receptor; GIP-R; Glucose-dependent insulinotropic polypeptide receptor; GIPR
    偶联
    Unconjugated
    分子量
    50.4 KDa
    剂型描述
    Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SEC-HPLC
    Greater than 85% as determined by SEC-HPLC. (QC verified)
    生物活性-ELISA
    Immobilized Recombinant Human GIPR(VLP) (Cat#C41R) at 10 μg/ml (100 μl/well) can bind Anti-Human GIPR mAb (Human IgG1). The ED50 of Anti-Human GIPR mAb (Human IgG1) is 6.61 ng/ml. (Regularly tested)
    运输条件
    • The product is shipped on dry ice/polar packs.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Store at ≤-70°C, stable for 6 months after receipt.
    • Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
    • Please minimize freeze-thaw cycles.
    产品背景
    GIP receptor (GIPR) belongs to the G-protein coupled receptor family, activating adenylate cyclase and increasing levels of intracellular cyclic adenosine monophosphate (cAMP) in pancreatic b cells, thereby stimulating insulin section glucosedependently. New discoveries of GIP receptor (GIPR) biology in adipose tissue, as well as findings that co-agonists for the glucagon-like peptide-1 receptor (GLP-1R) and GIPR induce greater weight loss than that seen with GLP-1R agonists alone, has led to continued interest in manipulating GIPR activity for the treatment of obesity/type 2 diabetes mellitus (T2DM).

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    图标文献和实验
    该产品被引用文献

    GIP receptor (GIPR) belongs to the G-protein coupled receptor family, activating adenylate cyclase and increasing levels of intracellular cyclic adenosine monophosphate (cAMP) in pancreatic b cells, thereby stimulating insulin section glucosedependently. New discoveries of GIP receptor (GIPR) biology in adipose tissue, as well as findings that co-agonists for the glucagon-like peptide-1 receptor (GLP-1R) and GIPR induce greater weight loss than that seen with GLP-1R agonists alone, has led to continued interest in manipulating GIPR activity for the treatment of obesity/type 2 diabetes mellitus (T2DM).

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    文献支持
    Human GIPR (VLP, Full Length)
    ¥840 - 17600