ARHGEF6 Homo sapiens Rac/Cdc42
guanine nucleotide exchange factor (GEF) 6, mRNA (cDNA clone MGC:49945 IMAGE:6015396).- 询价
- GeneCopoeia
- 广州
- GC-E0824
- 2025年07月16日
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- 技术资料
- 保存条件：
-20°C
- 保质期：
三年
- 英文名：
ARHGEF6 Homo sapiens Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6, mRNA (cDNA clone MGC:49945 IMAGE:6015396).
- 库存：
有
- 供应商：
GeneCopoeia
- 规格：
10μg
NCBI推荐的基因克隆供应商
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快—— 可直接用于蛋白表达，无需亚克隆步骤
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◆ Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3.2019. Cell, IF 31.398. The human cDNA library constructs coding ~5600 full-length plasma membrane protein and ~1000 secreted protein were purchased from GeneCopoeia.
◆ Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage. 2020. Cell, IF 30.17. OMICSLINK™ hPiezo1 ORF expression clone
◆ Identification of recurrent FHL2-GLI2 oncogenic fusion in sclerosing stromal tumors of the ovary. 2020. Nature Communications, IF 12.30. OMICSLINK™ wild type FHL2 , wild type and mutant GLI2, FHL2-GLI2 fusion ORF expression clones.
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文献和实验[1] Sanmarco, L.M., Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells. Nature, 2023. doi: 10.1038/s41586-023-06409-6
[2] Soto, J.S., et al. Astrocyte–neuron subproteomes and ob sessive–compulsive disorder mechanisms. Nature, 2023. doi: 10.1038/s41586-023-05927-7
[3] Turrell, F.K., et al. Age-associated microenvironmental changes highlight the role of PDGF-C in ER+ breast cancer metastatic relapse. Nature Cancer, 2023. doi: 10.1038/s43018-023-00525-y
[4] Wang, Y., et al. DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC. Nature Communications, 2023. doi: 10.1038/s41467-023-38160-x[5] Zheng, L., et al., The CD8α-PILRα interaction maintains CD8+ T cell quiescence. Science, 2022. doi: 10.1126/science.aaz8674
[资源] 所有的看家基因(housekeeping genes)列表+引物设计服务
guanine nucleotide exchange factor (GEF) 7 (ARHGEF7), transcript variant 1, mRNA 558 NM_003406 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ), transcript variant 1, mRNA 2008 NM_002419
／GDP交换因子(guanine exchange factor，GEF)，RalGDS激活RalA／B相关小GTP酶。RalBP，是一个GTP酶激活蛋白，它能抑制Cdc42和RacGTP酶，然后通过Rac／Cdc42调控激动蛋白细胞骨架的重组及转录因子NF―xB的活化，从而促进抗凋亡蛋白的产生来抑制细胞凋亡。 Ras信号转导通路 注：IKK：IκB激酶；ELK―l：ETS样蛋白―1；ERK：细胞外信号调节激酶；MEK．．MAPK／ERK激酶； caspase：半胱氨酸天冬
所有的看家基因(housekeeping genes)的列表+引物设计服务
Homo sapiens Rho-specific guanine nucleotide exchange factor p114 (P114-RHO-GEF), mRNA 405 NM_012423 Homo sapiens ribosomal protein L13a (RPL13A), mRNA 9545 NM_021128 Homo sapiens
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