Mterf1b Mus musculus mitochond
rial transcription termination factor 1b (Mterf1b), mRNA.- 询价
- GeneCopoeia
- 广州
- GC-Mm37194
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
三年
- 英文名：
Mus musculus mitochondrial transcription termination factor 1b (Mterf1b), mRNA.
- 库存：
有
- 供应商：
GeneCopoeia
- 规格：
10μg
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◆ Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3.2019. Cell, IF 31.398. The human cDNA library constructs coding ~5600 full-length plasma membrane protein and ~1000 secreted protein were purchased from GeneCopoeia.
◆ Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage. 2020. Cell, IF 30.17. OMICSLINK™ hPiezo1 ORF expression clone
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文献和实验[1] Sanmarco, L.M., Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells. Nature, 2023. doi: 10.1038/s41586-023-06409-6
[2] Soto, J.S., et al. Astrocyte–neuron subproteomes and ob sessive–compulsive disorder mechanisms. Nature, 2023. doi: 10.1038/s41586-023-05927-7
[3] Turrell, F.K., et al. Age-associated microenvironmental changes highlight the role of PDGF-C in ER+ breast cancer metastatic relapse. Nature Cancer, 2023. doi: 10.1038/s43018-023-00525-y
[4] Wang, Y., et al. DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC. Nature Communications, 2023. doi: 10.1038/s41467-023-38160-x[5] Zheng, L., et al., The CD8α-PILRα interaction maintains CD8+ T cell quiescence. Science, 2022. doi: 10.1126/science.aaz9448
Transcription System Using a HeLa Cell Mitochondrial Lysate
transcription from appropriate mtDNA templates (7 ), whereas the other makes use of a mitochondrial lysate programmed by exogenous templates (8 ) and supplemented, when necessary, with purified transcription termination factor (mTERF) (9 ). The rationale
mechanisms of its transcription, we have cloned the rat α1B -AR gene and identified its promoters and the cis -acting elements in its 5′ regulatory domain (2 ). Footprinting analyses using liver nuclear extracts have revealed a strongly protected region
的。 在许多生物中，编码基因的DNA编码区（coding region）只占了整个基因组的一小部分，其余均为非编码区，包括有激活和抑制基因转录的调控区域。因此，mRNA和蛋白的表达量可以得到精确调节。这种基因表达调控由一类被称为转录因子（transcription factor, TF）的蛋白完成，它们能够与基因附近（通常在基因上游）的非编码区内特定DNA模块结合，起到激活或者抑制基因表达的作用（图1A）。单个TF可以与许多不同的调节区结合，从而调节多个基因的转录。同一TF的结合位点有很高的序列相似性（图1B
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