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- 文献和实验
- 技术资料
- 供应商:
深圳中科百抗生物科技有限公司
- 库存:
大量
- 英文名:
Recombinant Human CD19(C-S)
- 规格:
100μg
CD19CD19是B细胞表达的一种CD分子(即白细胞分化抗原)。除浆细胞外的所有B细胞系,恶性B细胞与FDC(滤泡树突状细胞)都会表达该分子 。它是参与B细胞增殖、分化、活化及抗体产生的重要膜抗原,还可促进BCR的信号转导。
CD19为I型跨膜蛋白,具有单个跨膜结构域、胞内C末端和胞外N末端。胞外段含有两个C2型Ig样结构域。胞内结构域高度保守,由242个氨基酸组成,在C末端附近有9个酪氨酸残基。多项研究表明,CD19的生物学功能依赖于三个细胞质酪氨酸残基:Y391,Y482和Y513。
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文献和实验详见说说明书
Protocols for the preparation of tumour cells for s.c. injections in mice
) at 37 °C and 6% CO2 . The tumour models used in our laboratory are obtained by subcutaneous (s.c.) injection of the following cell lines in nude mice: C51 mouse colon adenocarcinoma FE-8 rat transformed fibroblasts F9 murine teratocarcinoma
Mutational Analysis of the Human Protein C Gene
The single gene for protein C is located at position q13–q14 on chromosome 2 (1 ). Two groups have described human genomic clones of protein C isolated from phage l charon libraries using cDNA for human protein C as hybridization probes
Human Intestinal Epithelial Response(s) to Clostridium difficile
suggest that C. difficile toxins A and B play a major role in the observed colonic inflammation and associated disease pathogenesis; however, the role of other potential bacterial factors at present remains unknown. Early effects of C. difficile on host
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