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文献和实验, a method is described that allows construction of multiantennary oligonucleotide glycoconjugates on a solid support. A bis(hydroxymethyl)malondiamide?based phosphoramidite that contains two phthaloyl?protected aminooxy groups compatible with normal chain
& Sons, Inc. Keywords: triazole?linkage; cycloaddition; phosphoramidite; solid?phase oligonucleotide synthesis GO TO THE FULL PROTOCOL: PDF or HTML
Synthesis of Oligodeoxynucleotides with 5′‐Caps Binding RNA Targets
phosphoramidite reagent, or assembled on the DNA chain. The step?wise assembly of the peptidyl chain is advantageous for combinatorial studies aimed at the optimization of a cap structure. The block coupling method, introducing the preassembled cap in one step
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