Sample:
Lane 1: Human HepG2 cell lysates
Lane 2: Human HeLa cell lysates
Primary: Anti-TMPRSS2 (bs-41361R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kDa
Observed band size: 58 kDa
- ￥1180 - 2800
- Bioss
- bs-41361R
- 2025年10月16日
- 产品信息以Bioss网站为准
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-41361R |
| 英文名称 | TMPRSS2 Rabbit pAb |
| 中文名称 | 丝氨酸蛋白酶10抗体 |
| 英文别名 | Epitheliasin; PRSS10; Serine protease 10; TMPRSS2; TMPRSS2 ERG FUSION GENE, INCLUDED; TMPRSS2 ETV1 FUSION GENE, INCLUDED; TMPS2_HUMAN; Transmembrane protease serine 2 catalytic chain; Transmembrane protease, serine 2; Transmembrane protease, serine 2, EC 3.4.219; Transmembrane protease, serine 2, EC 3.4.219; D16Ertd61e. |
| 产品应用 | WB=1:500-2000, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat) |
| 抗体来源 | Rabbit |
| 免疫原 | Recombinant human TMPRSS2 protein |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 54 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor biomarkers > Enzymes Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Serine protease > TMPRSS Neuroscience > Neurology process > Neurodegenerative disease |
| 亚细胞定位 | Cell membrane and Secreted. Activated by cleavage and secreted. |
| 组织特异性 | Expressed strongly in small intestine. Also expressed in prostate, colon, stomach and salivary gland. |
| 相似性 | Belongs to the peptidase S1 family. Contains 1 LDL-receptor class A domain. Contains 1 peptidase S1 domain. Contains 1 SRCR domain. |
| 功能 | Expressed strongly in small intestine. Also expressed in prostate, colon, stomach and salivary gland. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Extracellular proteases mediate the digestion of neiGHBoring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors (1,2). The TMPRSS2 gene encodes a 492 amino acid multimeric serine protease, which is mainly expressed in the mouse prostate and kidney, and is also expressed in the human small intestine, prostate, colon, stomach and salivary gland (3,4). TMPRSS2 contains several domains, including a serine protease domain of the S1 family, a scavenger receptor cysteine-rich domain of group A, an LDL receptor class A domain and a transmembrane domain (3). TMPRSS2 is expressed as a full length form and a cleaved protease domain (5) and its expression is increased by androgenic hormones. TMPRSS2 is also expressed in prostate carcinoma, suggesting that it may play a role in prostate carcinogenesis (6). |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {ELISA} | {1:5000-10000} |
Measured by its binding ability in a indirect ELISA. Immobilized Human TMPRSS2 protein, His Tag (Cat. bs-41361P) at 2 μg/mL (100 μL/well) can bind Rabbit Anti-Human TMPRSS2 Antibody, the EC50 is 118.5 ng/mL.
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[IF={{ 3.8 }}] {Mohamed Elbadawy. et al.Establishment of a bat lung organoid culture model for studying bat-derived infectious diseases.SCIENTIFIC REPORTS.2025 Feb 3;15(1):4035.} {IHC,IF} {}
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TMPRSS2 Rabbit pAb(bs-41361R)-50ul/100ul/200ul
￥1180 - 2800
