相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C
- 保质期:
6个月
- 英文名:
Human Progranulin Protein, His Tag, low endotoxin (MALS & SPR verified)
- 库存:
99
- 供应商:
Biorbyt
- 规格:
100 ug/1 mg
| 规格: | 100 ug | 产品价格: | ¥7631.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥44265.0 |
Progranulin, a secreted glycoprotein, is encoded in humans by the single GRN gene. Progranulin consists of seven and a half, tandemly repeated, non-identical copies of the 12 cysteine granulin motif. Many cellular processes and diseases are associated with this unique pleiotropic factor that include, but are not limited to, embryogenesis, tumorigenesis, inflammation, wound repair, neurodegeneration and lysosome function. Haploinsufficiency caused by autosomal dominant mutations within the GRN gene leads to frontotemporal lobar degeneration, a progressive neuronal atrophy that presents in patients as frontotemporal dementia.
产品名:Human Progranulin Protein, His Tag, low endotoxin (MALS & SPR verified)
货号:orb1786203
产品中文名:Human Progranulin Protein, His Tag, low endotoxin (MALS & SPR verified) 蛋白
产品详情链接:https://www.biorbyt.com/human-progranulin-protein-his-orb1786203.html
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验beads)结合细胞(刀豆蛋白 A 能与细胞膜上的糖蛋白结合)。使用非离子去污剂洋地黄皂苷进行细胞膜通透。然后分步孵育靶蛋白(如转录因子, TF)的抗体(一抗)、二抗、和 Protein A-Tn5 ,抗体和 Protein A-Tn5 能够通过细胞膜、核孔进入细胞核,Tn5 通过 Protein A 和抗体的介导切割靶蛋白附近的 DNA 序列。使用 Tn5 在进行切割的时候,会在被切割的片段两端加上接头序列,通过 PCR 扩增直接可以得到二代测序文库。 图 9: CUT&Tag、CUT
) in any given fraction have relevance to any human disease? If the protein has no obvious use as a drug target, it is ignored. If the protein is deemed relevant, one immediately has a lead molecule and a defined target. In cases where a single protein is eluted
-S10 柱子对于去污剂有高度的结合容量,比如每毫升固定的树脂可以结合 6 mg SDS 和 14 mg Triton® X-100。Table 1: A comparison of the detergent removal rates and percentage protein recovery with DetergentOUT™ GBS10. ag 蛋白的纯化 带有融合标签的表达产物----融合蛋白的纯化通常也是紧接细胞破碎工作进行的。设计融合标签的主要目的之一就是为了方便
技术资料暂无技术资料 索取技术资料










