- ￥4800
- Tanda
- TD-26381
- 美国
- 2025年11月07日
- ELISA, WB, IHC
- Mouse
- 脊椎动物
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
武汉天德
- 库存：
999
- 靶点：
D769H
- 级别：
科研级
- 目录编号：
TD-26381
- 克隆性：
单克隆
- 抗原来源：
蛋白
- 保质期：
24个月
- 抗体名：
ERBB2(D769H)
- 标记物：
FITC
- 宿主：
Mouse
- 适应物种：
脊椎动物
- 免疫原：
A synthetic peptide from the internal region of ERBB2 which includes the mutation of D769H, human origin.
- 亚型：
IgG
- 形态：
液体
- 应用范围：
ELISA, WB, IHC
- 保存条件：
-20℃
- 浓度：
1mg/ml
- 规格：
100μl
ERBB2(D769H)
| Cat. #: TD-26381 |
| Gene Symbol: ERBB2/HER2/Neu/c-Neu |
| Description: Anti-ERBB2(D769H) Mouse Monoclonal Antibody |
| Background: The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant tumors, especially with breast cancers. The expression level of Her2 is an important criteria in clinic evaluating of the progression of breast cancer. |
| Immunogen: A synthetic peptide from the internal region of ERBB2 which includes the mutation of D769H, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IF: 1:25-1:50 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes D769H mutant, but not wild type ERBB2 of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
Western blot analysis of recombinant ERBB2(D769H) and wild type proteins. Purified His-tagged ERBB2(D769H) protein (lane 1) and corresponding wild type protein (lane 2) were blotted with Anti-ERBB2(D769H) monoclonal antibody (Cat. #TD-26381).
Immunofluorescence:
Immunofluorescence of cells expressing ERBB2 proteins with Anti-ERBB2(D769H) antibody. HEK293T cells were transfected with pCDNA3-GFP-ERBB2 (WT) plasmid (left column) or pCDNA3-GFP-ERBB2(D769H) plasmid (right column), then fixed and stained with Anti-ERBB2(D769H) monoclonal antibody (Cat. #TD-26381).
|
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