- ￥7735
- Biorbyt
- orb1742691
- 英国
- 2025年07月13日
- WB
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
growth factor receptor bound protein 7 Antibody 抗体
- 抗体英文名：
growth factor receptor bound protein 7 Antibody
- 靶点：
growth factor receptor bound protein 7
- 浓度：
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 应用范围：
WB
- 宿主：
Rabbit
- 适应物种：
Human
- 保质期：
6-12个月
- 抗原来源：
详询
- 目录编号：
orb1742691
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
POLYCLONAL
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
- 形态：
Liquid
- 亚型：
IgG
- 免疫原：
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human GRB7. The exact sequence is proprietary.
- 规格：
100 ul
growth factor receptor bound protein 7 Antibody
产品名：growth factor receptor bound protein 7 Antibody
货号：orb1742691
产品中文名：growth factor receptor bound protein 7 Antibody 抗体
产品详情链接：https://www.biorbyt.com/growth-factor-receptor-bound-p-orb1742691.html
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文献和实验Grb2蛋白(growth factor receptor-bound protein 2)
Grb2是生长因子受体结合蛋白2,又叫Ash蛋白。该蛋白参与细胞内各种受体激活后的下游调节。它能够直接与激活的表皮生长因子受体磷酸化的酪氨酸结合,参与EGF受体介导的信号转导,也能通过与Shc磷酸化的酪氨酸结合间接参与由胰岛素受体介导的信号转导。Grb2能够同时与Shc、Sos结合形成Shc-Grb2-Sos复合物,并将Sos激活，激活的Sos与质膜上的Ras蛋白结合，并将其激活,引起信号级联反应。Grb2蛋白含有一个SH2结构域和两个SH3结构域,属SH蛋白。
Modulation of Growth Factor Receptor Expression by Irradiation for Immunotoxin Targeting
specific for them, are internalized by receptor-mediated endocytosis, and inhibit protein synthesis, causing apoptotic cell death (4 , 5 . The cytotoxic activity of the immunotoxin can be influenced by many factors, such as binding to the receptor
Dissecting the Epidermal Growth Factor Receptor Signal Transactivation Pathway
Interreceptor cross-talk has emerged as a general concept in cellular signaling cascades. Therein epidermal growth factor receptor (EGFR) signal transactivation represents the so far best investigated cross-talk mechanism comprising
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