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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
NME2 Antibody / Nucleoside diphosphate kinase B / NDKB 抗体
- 抗体英文名:
NME2 Antibody / Nucleoside diphosphate kinase B / NDKB
- 浓度:
详询
- 应用范围:
IHC-P, WB
- 宿主:
Mouse
- 适应物种:
Human
- 保质期:
6-12个月
- 抗原来源:
详询
- 目录编号:
orb1825029
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
Unconjugated
- 克隆性:
MONOCLONAL
- 保存条件:
Aliquot the NDKB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态:
详询
- 亚型:
Mouse IgG1, kappa
- 免疫原:
Recombinant full-length human protein was used as the immunogen for the NDKB antibody.
- 规格:
20 ug
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.
产品名:NME2 Antibody / Nucleoside diphosphate kinase B / NDKB
货号:orb1825029
产品中文名:NME2 Antibody / Nucleoside diphosphate kinase B / NDKB 抗体
产品详情链接:https://www.biorbyt.com/nme2-antibody-nucleoside-dip-orb1825029.html
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文献和实验X性联无丙种球蛋白血症(X-linked agammagl,bulinemia,XLA)是临床上首次确定的体液免疫缺陷病,由Brutor于1952年报道,故又称Bruton病。XLA作为常见的原发性免疫缺陷病之一,特点为血清中各类免疫球蛋白缺乏,或只能测得微量的抗体。外周血和淋巴组织中B细胞减少或完全缺乏,淋巴结中无生发中心和浆细胞。本病起病早,在出生数月后当患儿体内的母源性抗体水平下降时开始发病。临床表现为反复化脓性感染,患者细胞免疫功能不受影响(部分患者有T细胞数量减少),主要缺陷
Immunoprecipitation and Immune Complex kinase assay
9) Transfer to a new eppi tube and wash IP 3x with 500 microliters lysis buffer and then 1x with TN by spinning and resuspending. 10) If doing kinase assay, do additional wash in TN and then proceed with kinase assay (below). 11) Pellets can be stored dry
., Shen, X., and Shaw, B.R. 2008. Synthesis and properties of (alpha‐P‐borano)nucleoside 5′‐triphosphate analogues as potential antiviral agents. Nucleic Acids Symp. Ser. 52:81‐82.
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