- ￥3795
- Biorbyt
- orb1732990
- 英国
- 2025年07月09日
- IP, WB
- Rabbit
- Mouse, Rat
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- 详细信息
- 技术资料
- 抗体名：
Phospho-GSK3 (Tyr216/Tyr279) Antibody 抗体
- 抗体英文名：
Phospho-GSK3 (Tyr216/Tyr279) Antibody
- 浓度：
1mg/ml
- 应用范围：
IP, WB
- 宿主：
Rabbit
- 适应物种：
Mouse, Rat
- 保质期：
6-12个月
- 抗原来源：
详询
- 目录编号：
orb1732990
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
MONOCLONAL
- 保存条件：
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- 形态：
详询
- 亚型：
Rabbit IgG
- 免疫原：
A synthetic phosphopeptide corresponding to residues surrounding Tyr216 of human GSK3 alpha
- 规格：
100 ul
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation.
产品名：Phospho-GSK3 (Tyr216/Tyr279) Antibody
货号：orb1732990
产品中文名：Phospho-GSK3 (Tyr216/Tyr279) Antibody 抗体
产品详情链接：https://www.biorbyt.com/phospho-gsk3-tyr216tyr279-a-orb1732990.html
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Phospho-GSK3 (Tyr216/Tyr279) Antibody 抗体，orb1732990，Biorbyt
￥3795
