- ￥3795
- Biorbyt
- orb1731175
- 英国
- 2025年07月12日
- WB
- Rabbit
- Human, Rat
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- 详细信息
- 技术资料
- 抗体名：
Tight Junction Protein ZO 3 Antibody 抗体
- 抗体英文名：
Tight Junction Protein ZO 3 Antibody
- 浓度：
1mg/ml
- 应用范围：
WB
- 宿主：
Rabbit
- 适应物种：
Human, Rat
- 保质期：
6-12个月
- 抗原来源：
详询
- 目录编号：
orb1731175
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
MONOCLONAL
- 保存条件：
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- 形态：
详询
- 亚型：
Rabbit IgG
- 免疫原：
A synthetic peptide of human Zonula occludens protein 3
- 规格：
100 ul
TJP1, TJP2, and TJP3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton (PubMed:16129888). The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and basolateral plasma membrane domains of epithelial and endothelial cells. Binds and recruits PATJ to tight junctions where it connects and stabilizes apical and lateral components of tight junctions (PubMed:16129888). Promotes cell-cycle progression through the sequestration of cyclin D1 (CCND1) at tight junctions during mitosis which prevents CCND1 degradation during M-phase and enables S-phase transition (PubMed:21411630). With TJP1 and TJP2, participates to the junctional retention and stability of the transcription factor DBPA, but is not involved in its shuttling to the nucleus . Contrary to TJP2, TJP3 is dispensable for individual viability, embryonic development, epithelial differentiation, and the establishment of TJs, at least in the laboratory environment .
产品名：Tight Junction Protein ZO 3 Antibody
货号：orb1731175
产品中文名：Tight Junction Protein ZO 3 Antibody 抗体
产品详情链接：https://www.biorbyt.com/tight-junction-protein-zo-3-an-orb1731175.html
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Tight Junction Protein ZO 3 Antibody 抗体，orb1731175，Biorbyt
￥3795
