- ￥5265
- Biorbyt
- orb1823946
- 英国
- 2025年07月12日
- IHC-P
- Mouse
- Human
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- 详细信息
- 技术资料
- 抗体名：
MSH6 Antibody 抗体
- 抗体英文名：
MSH6 Antibody
- 浓度：
详询
- 应用范围：
IHC-P
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
6-12个月
- 抗原来源：
详询
- 目录编号：
orb1823946
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
RECOMBINANT
- 保存条件：
Aliquot the MSH6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态：
详询
- 亚型：
Mouse IgG1, kappa
- 免疫原：
A recombinant fragment of human MSH6 protein (within amino acids 1-200) was used as the immunogen for the MSH6 antibody.
- 规格：
20 ug
The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is an MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2.
产品名：MSH6 Antibody
货号：orb1823946
产品中文名：MSH6 Antibody 抗体
产品详情链接：https://www.biorbyt.com/msh6-antibody-orb1823946.html
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MSH6 Antibody 抗体，orb1823946，Biorbyt
￥5265
