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- 爱必信(absin)
- abs135685
- 上海
- 2025年07月15日
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- 详细信息
- 技术资料
- 库存：
99
- 供应商：
爱必信(上海)生物科技有限公司
- 保存条件：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
- 规格：
100ug/50ug
| 规格： | 100ug | 产品价格： | ￥2300.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥1500.0 |
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抗体描述： 产品名称：Rabbit anti-MSH6 Polyclonal Antibody 产品别名：MSH6抗体 宿主：Rabbit 反应种属：Human;Mouse;Rat 克隆性：Polyclonal Antibody 保存方法：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles 产品描述：The DNA mismatch repair system (MMR) repairs post-replication DNA, inhibits recombination between nonidentical DNA sequences, and induces both checkpoint and apoptotic responses following certain types of DNA damage (1). MSH2 (MutS homologue 2) forms the hMutS-α dimer with MSH6 and is an essential component of the mismatch repair process. hMutS-α is part of the BRCA1-associated surveillance complex (BASC), a complex that also contains BRCA1, MLH1, ATM, BLM, PMS2 proteins, and the Rad50-Mre11-NBS1 complex (2). Mutations in MSH6 and other MMR proteins have been found in a large proportion of hereditary nonpolyposis colorectal cancer (Lynch Syndrome), the most common form of inherited colorectal cancer in the Western world (3). Mutations in MSH6 have been shown to occur in glioblastoma in response to temozolomide therapy and to promote temozolomide resistance (4). 用途范围： WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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