重组人CD226蛋白|重组人白细胞分化抗原蛋白|白细胞分化抗

产品编号：KMP2308

产品名称：Human CD226 Protein, His Tag

中文名称： 重组人CD226蛋白

中文全称：重组人白细胞分化抗原蛋白

产品描述：产品描述：The Human CD226 Protein(KMP2308) is produced in HEK293 Cells and the target gene encoding Glu19-Asn247 is expressed with a 6His tag at the C-terminus.

产品别称：白细胞分化抗原, CD226 antigen, CD226

分子名称：CD226

预测分子量：80-90 kDa

物种：Human

宿主：HEK293 Cells

规格：20ug, 50ug, 100ug, 200ug, 1mg

纯化方式：Affinity purification

纯度：>95% as determined by SDS-PAGE

内毒素水平：<1.0 EU/ug determined by the LAL method

缓冲体系：PBS, pH7.4

Uniport:Q15762

产品背景：Human DNAX accessory molecule 1(DNAM-1/CD226) is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. Mature human DNAM-1 contains an extracellular domain(ECD) with two Ig-like C2-set domains and a cytoplasmic region that contains motifs for binding PDZ domains and band 4.1 family proteins. DNAM-1 is expressed on multiple lymphoid and myeloid cells and interacts with CD155 and CD112. Ligation of DNAM-1 promotes the activation of NK cells, CD8+ T cells, and mast cells, dendritic cell maturation, megakaryocyte and activated platelet adhesion to vascular endothelial cells, and monocyte extravasation; it inhibits the forrmation of osteoclasts. Plateletendothelium, interactions mediated by DNAM-1, enable the metastasis of tumor cells to the lung.

保存条件：Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.

运输条件：In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.

说明：This product is for research use only.