Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
英文名:
Human CD152 Protein, Fc Tag, Avi Tag
库存:
999
供应商:
卡梅德生物科技(天津)有限公司
规格:
20ug/100ug
规格:
20ug
产品价格:
¥3680.0
规格:
100ug
产品价格:
¥9936.0
产品编号: KMP2303产品名称: Human CD152 Protein, Fc Tag, Avi Tag中文名称: 重组人CD152蛋白中文全称: 重组人细胞毒T淋巴细胞相关抗原蛋白关键词: 细胞毒T淋巴细胞相关抗原, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, Ctla4, Human CD152 Protein, Fc Tag, Avi Tag, Recombinant Protein, KMP2303物种: Human宿主: HEK293 Cells规格: 50ug, 100ug, 200ug纯化方式: Affinity purification纯度: >95% as determined by SDS-PAGE内毒素水平: <1.0 EU/ug determined by the LAL method缓冲体系: PBS, pH7.4Uniprot: P16410SDS-PAGE: KMP2303 SDS-PAGE image1.png功能: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.产品背景: Cytotoxic T-lymphocyte protein 4, is a single-pass type I membrane protein. It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin(Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.保存条件: Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.运输条件: In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.说明: This product is for research use only.官网链接: https://www.kmdbioscience.cn/参考文献: 1.Annu. Rev. Immunol. 24:65-97 (2006) 2.J. Exp. Med. 174:561-569 (1991)