- ￥1960
- BOSTER
- A12216-100ul
- 中国
- 2025年07月10日
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- 库存：
大量
- 供应商：
广州威佳科技有限公司
- 规格：
100ul
产品概况
| 货号 | A12216 |
|---|---|
| 产品名称 | Anti-WDR24 Antibody |
| 基因名 | WDR24 |
| 抗体来源 | Rabbit |
| 克隆 | Polyclonal |
| 抗体亚型 | Rabbit IgG |
| 免疫原 | E.coli-derived human WDR24 recombinant protein (Position: H309-H762). |
| 内容 | 500 ug/ml antibody with PBS，0.02% NaN3, 1 mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500 ug/ml |
| 产品形态 | Liquid |
| 保存条件 | 12 months from date of receipt, -20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| 背景资料 | WD repeat-containing protein 24 is a protein that in humans is encoded by the WDR24 gene. WDR24 is a component ofthe GATOR2 complex which hasfive known subunits(WDR24, WDR59, Mios, Sec13, and Seh1L). GATOR2 complex positively regulates mTORC1 signaling by acting upstream of orin parallel to GATOR1, which is a GTPase-activating protein (GAP) for RagA or RagB and an inhibitor ofthe amino-acid-sensing pathway. |
| 研究类别 | 1. Robert, A. , Saxton, Kevin, E. , Knockenhauer, Rachel, L. , & Wolfson, et al. (2016). Structural basis for leucine sensing by the sestrin2-mtorc1 pathway. Science (New York, N.Y.).2. Wolfson, R. L. , Chantranupong, L. , Saxton, R. A. , Kuang, S. , Scaria, S. M. , & Cantor, J. R. , et al. (2016). [Research Article] Sestrin2 is a leucine sensor for the mTORC1 pathway.3. Wang, D., Xu, C., Yang, W., Chen, J., Ou, Y., Guan, Y., ... & Liu, Y. (2022). E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression. Molecular Cell, 82(4), 770-784. |
| Uniprot ID | WDR24: Q96S15 |
| 推荐配套的二抗和检测试剂 | Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot. |
产品应用细节
为了提供优质的抗体，博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
| 应用 | 稀释度* |
|---|---|
| Western blot (WB): | 1:500-2000 |
| ELISA: | 1:100-1000 |
*稀释度需要用户自己调试，此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
产品图片描述
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[list_product_images]Figure 1. Western blot analysis of anti- WDR24 antibody (A12216). The sample well of each lane was loaded with 30ug of sample under reducing conditions.
Lane 1: rat brain tissue lysates,
Lane 2: mouse brain tissue lysates,
Lane 3: mouse thymus tissue lysates.
Use rabbit anti- WDR24 1:1000, probed with a goat anti-rabbit IgG-HRP secondary antibody. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog#EK1002). A specific band was detected for WDR24 at approximately 88KD. The expected band size for WDR24 is at 88KD.[/list_product_images]
Lane 1: rat brain tissue lysates,
Lane 2: mouse brain tissue lysates,
Lane 3: mouse thymus tissue lysates.
Use rabbit anti- WDR24 1:1000, probed with a goat anti-rabbit IgG-HRP secondary antibody. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog#EK1002). A specific band was detected for WDR24 at approximately 88KD. The expected band size for WDR24 is at 88KD.[/list_product_images]
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Anti-WDR24 Antibody(A12216-100ul)
￥1960
