- ￥1960
- BOSTER
- A11941-1-100ul
- 中国
- 2025年07月09日
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- 详细信息
- 技术资料
- 库存：
大量
- 供应商：
广州威佳科技有限公司
- 规格：
100ul
产品概况
| 货号 | A11941-1 |
|---|---|
| 产品名称 | Anti-ST6GALNAC4 Antibody |
| 基因名 | ST6GALNAC4 |
| 抗体来源 | Rabbit |
| 抗体亚型 | Rabbit IgG |
| 免疫原 | E.coli-derived human ST6GALNAC4 recombinant protein (Position: D39-T302). |
| 内容 | 500 ug/ml antibody with PBS，0.02% NaN3, 1 mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500 ug/ml |
| 产品形态 | Liquid |
| 保存条件 | 12 months from date of receipt, -20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| 背景资料 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4, also known as sialyltransferase 3C (SIAT3-C) or sialyltransferase 7D (SIAT7-D) is a sialyltransferase enzyme that in humans is encoded by the ST6GALNAC4 gene. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. Readthrough transcripts exist for this gene and the downstream ST6GALNAC6 gene. |
| 研究类别 | 1. Gilley, J., Fried, M. Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes. Hum. Molec. Genet. 8: 1313-1320, 1999. 2. Harduin-Lepers, A., Stokes, D. C., Steelant, W. F. A., Samyn-Petit, B., Krzewinski-Recchi, M.-A., Vallejo-Ruiz, V., Zanetta, J.-P., Auge, C., Delannoy, P. Cloning, expression and gene organization of a human Neu5Ac-alpha-2-3Gal-beta-1-3GalNAc alpha-2,6-sialyltransferase: hST6GalNAc IV. Biochem. J. 352: 37-48, 2000. 3. Kim, S.-W., Kang, N.-Y., Lee, S.-H., Kim, K.-W., Kim, K.-S., Lee, J.-H., Kim, C.-H., Lee, Y.-C. Genomic structure and promoter analysis of human NeuAc alpha-2,3Gal beta-1,3GalNAc alpha-2,6-sialyltransferase (hST6GalNAc IV) gene. Gene 305: 113-120, 2003. |
| Uniprot ID | ST6GALNAC4: Q9H4F1 |
| 推荐配套的二抗和检测试剂 | Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for ICC. |
产品应用细节
为了提供优质的抗体，博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
| 应用 | 稀释度* |
|---|---|
| Western blot (WB): | 1:500-2000 |
| ELISA: | 1:100-1000 |
*稀释度需要用户自己调试，此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
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Anti-ST6GALNAC4 Antibody(A11941-1-100ul)
￥1960
