Anti-APRIL/TNFSF13 Antibody(A02417-2-100ul)

Anti-APRIL/TNFSF13 Antibody(A0

2417-2-100ul)
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  • ¥1960
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  • A02417-2-100ul
  • 中国
  • 2025年07月05日
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    • 详细信息
    • 技术资料
    • 库存

      大量

    • 供应商

      广州威佳科技有限公司

    • 规格

      100ul

    产品概况

    货号 A02417-2
    产品名称 Anti-APRIL/TNFSF13 Antibody
    基因名 TNFSF13
    抗体来源 Rabbit
    克隆 Polyclonal
    抗体亚型 Rabbit IgG
    分子量 32KD
    免疫原 E.coli-derived human APRIL/TNFSF13 recombinant protein (Position: M1-L250).
    内容 500 ug/ml antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
    纯化方式 Immunogen affinity purified.
    浓度 500 ug/ml
    产品形态 Liquid
    保存条件 12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
    背景资料 A proliferation-inducing ligand (APRIL), also known as tumor necrosis factor ligand superfamily member 13 (TNFSF13), is a protein of the TNF superfamily recognized by the cell surface receptor TACI. The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. And this protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
    研究类别 1. "Entrez Gene: TNFSF13 tumor necrosis factor (ligand) superfamily, member 13".2. Hahne M, Kataoka T, Schr?ter M, Hofmann K, Irmler M, Bodmer JL et al. (Sep 1998). "APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth". The Journal of Experimental Medicine 188 (6): 1185–90.
    Uniprot ID TNFSF13: O75888
    推荐配套的二抗和检测试剂 Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

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    [list_product_images]Figure 1. Western blot analysis of anti- APRIL/TNFSF13 antibody (A02417-2). The sample well of each lane was loaded with 50ug of sample under reducing conditions.
    Lane 1: human U-937 whole cell lysates.
    Use rabbit anti- APRIL/TNFSF13 1:1000, probed with a goat anti-rabbit IgG-HRP secondary antibody. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002). A specific band was detected for APRIL/TNFSF13 at approximately 32KD. The expected band size for APRIL/TNFSF13 is at 27KD.[/list_product_images]

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