- ￥1960
- BOSTER
- A07411-1-100ul
- 中国
- 2025年07月11日
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- 详细信息
- 技术资料
- 库存：
大量
- 供应商：
广州威佳科技有限公司
- 规格：
100ul
产品概况
| 货号 | A07411-1 |
|---|---|
| 产品名称 | Anti-ORAI2 Antibody |
| 基因名 | ORAI2 |
| 抗体来源 | Rabbit |
| 克隆 | Polyclonal |
| 抗体亚型 | Rabbit IgG |
| 分子量 | 39KD |
| 免疫原 | E.coli-derived human ORAI2 recombinant protein (Position: H21-L254). |
| 内容 | 500 ug/ml antibody with PBS ，0.02% NaN3 , 1 mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500 ug/ml |
| 产品形态 | Liquid |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| 背景资料 | Protein orai-2 is a protein that in humans is encoded by the ORAI2 gene. ORAI2 transcripts are predominantly expressed in kidney, lung, and spleen, and it appears that ORAI2 is the only ORAI isoform with multiple transcripts. Co-expresssion of ORAI2 and STIM1 was shown to produce currents that appear similar but smaller than those produced by co-expression of ORAI1 and STIM1. |
| 研究类别 | 1. Feske, S., Gwack, Y., Prakriya, M., Srikanth, S., Puppel, S.-H., Tanasa, B., Hogan, P. G., Lewis, R. S., Daly, M., Rao, A. A mutation in ORAI1 causes immune deficiency by abrogating CRAC channel function. Nature 441: 179-185, 2006.2. Mercer, J. C., DeHaven, W. I., Smyth, J. T., Wedel, B., Boyles, R. R., Bird, G. S., Putney, J. W., Jr. Large store-operated calcium selective currents due to co-expression of ORAI1 or ORAI2 with the intracellular calcium sensor, Stim1. J. Biol. Chem. 281: 24979-24990, 2006. |
| Uniprot ID | ORAI2: Q96SN7 |
| 推荐配套的二抗和检测试剂 | Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot. |
产品应用细节
为了提供优质的抗体，博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
| 应用 | 稀释度* |
|---|---|
| Western blot (WB): | 1:500-2000 |
| ELISA： | 1:100-1000 |
*稀释度需要用户自己调试，此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
产品图片描述
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[list_product_images]Figure 1. Western blot analysis of anti- ORAI2 antibody (A07411-1). The sample well of each lane was loaded with 50ug of sample under reducing conditions.Lane 1: human A375 whole cell lysates,Lane 2: human Jurkat whole cell lysates,Lane 3: human hepg2 whole cell lysates.Lane 4: human K562 whole cell lysates,Use rabbit anti- ORAI2 1:1000, probed with a goat anti-rabbit IgG-HRP secondary antibody. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002). A specific band was detected for ORAI2 at approximately 39KD. The expected band size for ORAI2 at 39KD.[/list_product_images]
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Anti-Orai2 Antibody(A07411-1-100ul)
￥1960
