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- 规格:
250ug
Animal-Free Murine IL-21 (250ug)
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Product Details |
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Size |
250 µg |
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Species |
Mouse |
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Published Species |
Mouse |
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Expression system |
E. coli |
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Amino acid sequence |
MHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLS |
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Molecular weight |
15 kDa |
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Class |
Recombinant |
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Type |
Protein |
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Purity |
98% by SDS-PAGE gel and HPLC analyses. |
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Endotoxin concentration |
<0.1 EU/µg |
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Activity |
Determined by its ability to stimulate the proliferation of human ANBL-6 cells. The expected ED50 is 1.0 ng/ml, corresponding to a specific activity of 1 x 10^6 units/mg. |
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Conjugate |
Unconjugated |
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Form |
Lyophilized |
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Purification |
purified |
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Contains |
no preservative |
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Storage conditions |
-20°C |
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Applications |
Tested Dilution |
Publications |
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Functional Assay (Functional) |
Assay-dependent |
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In vitro Assay (IV) |
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2 Publications |
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Product Specific Information
Recombinant Murine IL-21 is a 15.0 kDa protein consisting of 130 amino acid residues.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot- specific Certificate of Analysis
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文献和实验[1]Ricker E, Manni M, Flores-Castro D, Jenkins D, Gupta S, Rivera-Correa J, Meng W, Rosenfeld AM, Pannellini T, Bachu M, Chinenov Y, Sculco PK, Jessberger R, Prak ETL, Pernis AB. Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice. Nat Commun. 2021 Aug 10;12(1):4813. doi: 10.1038/s41467-021-25102-8. PMID: 34376664; PMCID: PMC8355159.
[2]Takahara T, Matsuo K, Seto M, Nakamura S, Tsuzuki S. Synergistic activity of Card11 mutant and Bcl6 in the development of diffuse large B-cell lymphoma in a mouse model. Cancer Sci. 2016 Nov;107(11):1572-1580. doi: 10.1111/cas.13057. Epub 2016 Nov 4. PMID: 27560392; PMCID: PMC5132338.
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