小鼠肺微血管内皮细胞
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小鼠肺微血管内皮细胞

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  • ¥3660
  • 南京万木春生物
  • 进口/国产
  • WM-24JY548
  • 2025年12月13日
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 英文名

      /

    • 库存

      现货库存

    • 供应商

      /

    • 肿瘤类型

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    • 细胞类型

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    • 品系

      /

    • 组织来源

      ATCC/DSMZ/ECACC

    • 相关疾病

      /

    • 物种来源

      人或动物

    • 免疫类型

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    • 细胞形态

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    • 是否是肿瘤细胞

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    • 器官来源

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    • 运输方式

      常温或干冰

    • 年限

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    • 生长状态

      /

    • 规格

      T25

    小鼠肺微血管内皮细胞

    种属

    小鼠

    组织来源

    正常肺组织

    传代比例

    1:2传代

    完全培养基配置

    基础培养基500ml ;生长添加剂5ml ;胎牛血清25ml ;双抗5ml

    简介

    肺微血管内皮细胞构成半选择性屏障 ,该屏障对于肺气体交换 ,调节液体和可溶物在血液与肺间质之间的流动具有重 要意义。它还具有代谢功能 ,可以执行一定的非呼吸功能。在肺损伤中 ,肺微血管内皮细胞是活性氧类的重要靶细胞 之一。在肺炎的发生过程中 ,神经体液介质和氧化剂作用于内皮细胞 ,使得细胞间隙渗透性增加 ,蛋白质由血液进入 间质。细胞间隙渗透性的增加导致低氧血症 ,出现成人呼吸窘迫综合征和非心源性肺水肿。

    形态

    上皮细胞样 ,多角形细胞样

    生长特征

    贴壁生长

    细胞检测

    CD31免疫荧光染色为阳性免疫荧光鉴定 ,细胞纯度可达90%以上 ,不含有HIV-1、HBV、HCV、支原体、细菌、酵 母和真菌等。

    倍增时间

    每周 2 至 3 

    换液频率

    2-3天换液一次

    培养条件

    气相 :空气 ,95% ;二氧化碳 ,5%。 温度 :37摄氏度 ,培养箱湿度为70%-80%。

    冻存条件

    冻存液 :90%FBS ,DMSO 10%,

    或使用非程序冻存液 :官网货号JY-H040

    产品使用

    仅限于科学研究 ,不可作为动物或人类疾病的治疗产品使用。

    cancer genomics data. We compared expression and enrichment levels of 787 immune-related genes and 23 immune gene-sets among TP53-mutated GCs, TP53-wildtype GCs, and normal tissue, and explored the correlations between p53-mediated pathways and immune activities in  clinical validation; 3. perspectives on how to realize the potential of machine learning models and to overcome the perceptual and practical limits of visual scoring.Autologous tumor cell-based vaccines (ATVs) are emerging as a transformable approach for personalized immunotherapy, but  patients were treated with ERT/αPD-1 or plus chemotherapy. Radiation-induced pneumonitis occurred in 1 of 26 patients receiving thoracic ERT. There were two cases of grade III toxicity  cancer-associated fibroblasts, but also immune cells of both the innate and adaptive system (tumour-associated macrophages, neutrophils, natural killer cells, and T and B lymphocytes), and  

    Questions/purposes: Our objectives were (I) characterize the epidemiology of de novo bone metastasis with respect to patient demographics, (II) characterize the incidence by primary site, age, and sex (2010-2015), and (III) compare survival of de novo metastatic cancer patients with and without bone metastasis.

    Methods: This is a retrospective, population-based study using nationally representative data from the Surveillance, Epidemiology, and End Results program, 2010-2015. Incidence rates by year of diagnosis, annual percentage changes, Kaplan-Meier, univariate and multiple Cox regression models are included in the analysis.

    Results: Of patients with cancer in the SEER database, 5.1% were diagnosed with metastasis to bone, equaling ~18.8 per 100,000 bone metastasis diagnoses in the US per year (2010-2015). For adults >25, lung cancer is the most common primary site (2015 rate: 8.7 per 100,000) with de novo bone metastases, then prostate and breast primaries (2015 rates: 3.19 and 2.38 per 100,000, respectively). For patients <20 years old, endocrine cancers and soft tissue sarcomas are the most common primaries. Incidence is increasing for prostate (Annual Percentage Change (APC) = 4.6%, P < 0.001) and stomach (APC = 5.0%, P = 0.001) cancers. The presence of de novo bone metastasis was associated with a limited reduction in overall survival (HR = 1.02, 95%, CI = [1.01-1.03], p < 0.001) when compared to patients with other non-bone metastases.






     

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    /responders to GC immunotherapy. TP53 mutations frequently occur in GC and are associated with unfavorable clinical outcomes in GC. We performed a comprehensive characterization of the associations between TP53 mutations and immune activities in GC based on two large-scale GC

    Autoimmune and Infectious Diseases

    Concerning autoimmune diseases (e.g., RA and MS) and chronic infectious diseases like TB, can autophagy modulation ameliorate disease  progression?  Targeting  autophagy  in  several  animal models of

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