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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
/
- 库存:
现货库存
- 供应商:
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- 肿瘤类型:
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- 细胞类型:
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- 品系:
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- 组织来源:
ATCC/DSMZ/ECACC
- 相关疾病:
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- 物种来源:
人或动物
- 免疫类型:
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- 细胞形态:
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- 是否是肿瘤细胞:
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- 器官来源:
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- 运输方式:
常温或干冰
- 年限:
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- 生长状态:
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- 规格:
T25
| 种属 | 人 |
| 组织来源 | 正常胆管组织 |
| 传代比例 | 1:2传代 |
| 完全培养基配置 | 基础培养基500ml ;生长添加剂5ml ;胎牛血清10ml ;双抗5ml |
| 简介 | 胆管 ,输送胆汁的管道。由肝分泌的胆汁 ,经肝左、右管、肝总管、胆囊管进入胆囊贮存 ,肝内胆管的部分包括 : 左、右肝管;左内叶、左外叶、右前叶、右后叶胆管;各肝段胆管;小叶间胆管;毛细胆管 ,常见的胆管病变如胆道 闭塞、原发性硬化性胆管炎、胆管癌等 ,都是以胆管上皮为病变靶位 ,因此研究胆管上皮细胞的生物学特性和病理变 化有重要意义。在这些病变过程中 ,肝内胆管上皮常暴露于常暴露于较高炎症因子中 ,会表现细胞损伤和继发性增值 为特征的病理变化。 |
| 形态 | 上皮细胞样 ,多角形细胞样 |
| 生长特征 | 贴壁生长 |
| 细胞检测 | 细胞角蛋白19( CK-19 )免疫荧光染色为阳性免疫荧光鉴定 ,细胞纯度可达90%以上 ,不含有HIV-1、HBV、 HCV、支原体、细菌、酵母和真菌等。 |
Interventional radiology plays a significant role in the treatment of bone metastases by various techniques, percutaneous or endovascular. Vertebroplasty is the most well-studied technique for stabilisation of spine metastases as it induces satisfactory stabilisation of the vertebra and offers clear improvement of the quality of life. Due to the success of this technique cementoplasty of other bones, mainly pelvic girdle, has been largely developed. The development of reinforced cementoplasty allows treatment of pre-fractural osteolysis of some long bones. The heat due to the polymerisation of the cement induces carcinolytic effect but this effect is not as important as that which results from radiofrequency destruction. This last technique appears currently as the most important development to definitively destroy bone metastases and is progressively replacing percutaneous alcoholic destruction of such lesions. Angiographic techniques, such as endovascular embolisation, can also be very useful to reduce the risk of surgical treatment of hyper vascular metastases. Chemoembolisation is currently developed to associate pain relief induced by Endovascular embolisation and the carcinolytic effect obtained by local endovascular chemotherapy. All these techniques should develop largely during the next years.
EurJImmunol,2021,51(9) :2137- 2150.on FDA-approved immunotherapies for these cancers, as well as a short discussion of the many therapeutic and scientific challenges ahead in order to optimize the uses of this new class of drug.Background: With numerous and fast approvals of different agents including immune checkpoint inhibitors, monoclonal antibodies, or chimeric antigen receptor (CAR) T-cell therapy,
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文献和实验/ZHANG W Q, LIU X, ZHU Y C, et al.
Transcriptional and posttranslational
regulation ofTh17/Treg balance in health anddisease[J] .
EurJImmunol,2021,51(9) :2137- 2150.
肝外胆管癌是指左右肝管、肝总管、胰腺上胆总管的原发恶性肿瘤,通常不包括位于壶腹部和乳头部的癌肿多发生于肝外胆管任何部位,但肝门部胆管癌(Klatskin氏肿瘤)约占50%以上。进行性梗阻性黄疸为本病的主要临床症状。本病病因至今尚不清楚,约有16%-30%的胆管癌病人伴有胆结石,故结石的慢性刺激被认为可能是一个致癌因素;先天性胆总管囊肿病人胆管癌发生率高;胆管良性乳头状瘤可转变为胆管癌,原发性硬化胆管炎合并溃疡性结肠炎者发生胆管癌的比例高,有报告0.4-1.4%。胆道血吸
肝外胆管正常只不过一条长约10cm,外径不足1cm的胆汁转输通道。其位置深在,位于肝脏、十二指肠等组织器官之后。因此,在腹部外伤中,单纯肝外胆管损伤少见,多并发于肝、十二指肠的损伤。在处理肝、十二指肠损伤时,应警惕肝外胆管损伤的存在,并予以仔细的探查,以免遗漏。 临床表现 1.腹部剧痛,以右上腹为主,逐渐延及全腹,伴有恶心、呕吐。 2.胆汁性腹膜炎征象,腹肌紧张、明显压痛反跳痛。 3.并发腹腔内其他脏器损伤者,可有相应的症状和体征出现。 诊断
肝外胆管损伤及狭窄修复术 胆管缺如和胆管狭窄,有的属先天性畸形,但多数系手术误伤所致。胆管缺损修建术可分两类:一类适用于较小的胆管缺损,如胆管部分狭窄修复术、胆管端端吻合术;另一类适用于较大的胆管缺损,如胆管十二指肠吻合术、肝外胆管空肠端端吻合术。胆管修建术比较复杂、困难,应根据病人的病情严格掌握适应证。由于胆管再次手术修建更加困难,应争取一期完成手术,仅在必要时分两期进行,第一期引流胆管,第二期修建胆管。 [适应证] 1.由于手术或外伤引起
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