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- PA6515
- 湖北武汉
- 2025年07月14日
- IHC-P
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- Human
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
Topoisomerase IIα Monoclonal Antibody_货号:PA6515_即用型抗体
- 抗体英文名：
Topoisomerase IIα Monoclonal Antibody
- 应用范围：
IHC-P
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
12个月
- 目录编号：
PA6515
- 级别：
科研级别
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 标记物：
Unconjugated
- 克隆性：
Monoclonal
- 保存条件：
The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months.
- 形态：
液体
- 规格：
200μL/100μL/6mL/3mL
| 规格： | 200μL | 产品价格： | ￥3249.0 |
|---|---|---|---|
| 规格： | 100μL | 产品价格： | ￥1932.0 |
| 规格： | 6mL | 产品价格： | ￥648.0 |
| 规格： | 3mL | 产品价格： | ￥360.0 |
货号：PA6515
| Verified Samples |
Verified Samples in IHC:Human tonsil tissue
|
| Size |
3mL/6mL(即用型);100μL/200μL(浓缩型)
|
| Clonality |
Monoclonal
|
| Abbre |
Topoisomerase IIα
|
| Synonyms |
alpha isozyme,ATP hydrolyzing DNA topoisomerase II alfa,DNA gyrase,DNA topoisomerase (ATP hydrolyzing),DNA topoisomerase 2 alpha,DNA topoisomerase 2-alpha,DNA topoisomerase II 170 kD,DNA topoisomerase II alpha isozyme,DNA topoisomerase II,DNA Topoisomerase2,TOP 2A,TOP2,TOP2A,TOP2A,Topoisomerase DNA II alpha 170kDa,TP2A
|
| Swissprot |
P11388
|
| Cellular Localization |
Nucleus
|
| Storage |
The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months.
|
| Clone No. |
YN01636m
|
| Conjugation |
Unconjugated
|
| Background |
TOPOⅡ是一种核内酶，是某些肿瘤药物的靶分子。同时与细胞的信号传导、细胞增殖以及细胞凋亡有关。TOPOⅡ表达水平越高，对肿瘤药物敏感性越高。目前多用于肿瘤耐药的研究。
|
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文献详情查看>>>>
Topoisomerase I and II Activity Assays
DNA topoisomerases I and II (top1 and top2, respectively) are ubiquitous enzymes that play an essential role in transcription, replication, chromosome segregation, and DNA repair. The basic enzymatic reaction of topoisomerases
Assaying Topoisomerase II Checkpoints in Yeast
Topoisomerase II activity is crucial to maintain genome stability through the removal of catenanes in the DNA formed during DNA replication and scaffolding the mitotic chromosome. Perturbed Topo II activity causes defects in chromosome
Depletion and Mutation of Topoisomerase II in Animal Cells
Eukaryotic type II topoisomerases (Topo II) are implicated in a wide range of cellular processes. Cells in which Topo II protein has been specifically depleted or mutated provide powerful systems for analysing the normal in vivo functions
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