- ￥1380 - 3300
- Elabscience
- 湖北武汉
- E-AB-70069
- 2025年10月22日
- IHC
- Rabbit
- Human;Rat
企业认证
相关产品推荐更多 >
![PE/Cyanine5.5 Anti-Human HLA-DR 抗体流式抗体[L243]](https://img1.dxycdn.com/p/s14/2024/0123/331/2156982385673069471.jpg!wh200)
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human;Rat
- 保质期：
12个月
- 级别：
科研
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 抗体英文名：
p27 Polyclonal Antibody
- 抗体名：
p27 Polyclonal Antibody_货号:E-AB-70069_多克隆抗体
- 规格：
200μL/120μL/60μL
| 规格： | 200μL | 产品价格： | ￥3300.0 |
|---|---|---|---|
| 规格： | 120μL | 产品价格： | ￥2220.0 |
| 规格： | 60μL | 产品价格： | ￥1380.0 |
p27 Polyclonal Antibody
| Verified Samples |
Verified Samples in IHC: Human lung cancer, Human liver cancer, Rat spleen cancer, Human prostate
|
| Dilution |
IHC 1:100-1:400
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse P27 KIP1
|
| Abbre |
p27
|
| Synonyms |
AA408329, AI843786, CDKN 1B, CDKN 4, CDKN1B, CDKN4, CDN1B, Cdki1b, Cyclin Dependent Kinase Inhibitor 1B, Cyclin dependent kinase inhibitor p27, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor 1B (p27, Cyclin-dependent kinase inhibitor p2, Kip1)
|
| Swissprot |
P46527, P46414
|
| Cellular Localization |
Nucleus. Cytoplasm. Endosome. Nuclear and cytoplasmic in quiescent cells. AKT-or RSK-mediated phosphorylation on Thr-198, binds 14-3-3, translocates to the cytoplasm and promotes cell cycle progression. Mitogen-activated UHMK1 phosphorylation on Ser-10 also results in translocation to the cytoplasm and cell cycle progression. Phosphorylation on Ser-10 facilitates nuclear export. Translocates to the nucleus on phosphorylation of Tyr-88 and Tyr-89. Colocalizes at the endosome with SNX6 and this leads to lysosomal degradation.
|
| Concentration |
0.89 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4.
|
| Purification Method |
Affinity purification
|
| Research Areas |
Cancer, Cell Biology, Epigenetics and Nuclear Signaling
|
| Conjugation |
Unconjugated
|
| Background |
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).
|
p27 Polyclonal AntibodyElabscience®提供8000+经过实验验证的高品质一抗，主要包括： 流式抗体、 单抗、 多抗、 重组抗体、 内参/标签抗体、 乙酰化/磷酸化/甲基化抗体、 磁珠/凝胶偶连抗体、 病毒抗体等。
p27 Polyclonal AntibodyStore at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
p27 Polyclonal Antibody产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Novel pH-sensitive and biodegradable micelles for the combined delivery of doxorubicin and conferone to induce apoptosis in MDA-MB-231 breast cancer cell line
IF:3.119
Journal:RSC Advances
DOI:10.1039/D0RA03467C
Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
then serially diluted in 100 µl assay buffer on the plate). Incubate @ RT for 1 hr while shaking. Meanwhile let TMB solution equilibrate to RT. Wash plate 3x and add 100 µl/well rabbit polyclonal anti-p27 antibody diluted 1:1000 in assay buffer
Construction of Polyclonal Antibody Libraries Using Phage Display
Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified
技术资料暂无技术资料 索取技术资料
