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SNCA Polyclonal Antibody_货号:E-AB-70302_多克隆抗体
SNCA Polyclonal Antibody
WB
Rabbit
Human;Mouse;Rat
12个月
E-AB-70302
科研级别
999
武汉伊莱瑞特生物科技股份有限公司
Unconjugated
Polyclonal
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
液体
IgG
200μL/120μL/60μL
规格: | 200μL | 产品价格: | ¥3300.0 |
---|---|---|---|
规格: | 120μL | 产品价格: | ¥2220.0 |
规格: | 60μL | 产品价格: | ¥1380.0 |
Verified Samples |
Verified Samples in WB:U87,SH-SY5Y,Mouse brain,Mouse cerebral cortex,Rat brain,Rat cerebral cortex
|
Dilution |
WB 1:500-1:2000
|
Clonality |
Polyclonal
|
Isotype |
IgG
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse α-synuclein
|
Abbre |
SNCA
|
Synonyms |
Alpha synuclein;Alpha-synuclein;Alpha-synuclein;isoform NACP140;alphaSYN;MGC105443;MGC110988;MGC127560;MGC64356;NACP;Non A beta component of AD amyloid;Non A4 component of amyloid;Non A4 component of amyloid precursor;Non-A beta component of AD amyloid;Non-A-beta component of alzheimers disease amyloid;precursor of;Non-A4 component of amyloid precursor;Non-A4 component of amyloid;precursor of;OTTHUMP00000218549;OTTHUMP00000218551;OTTHUMP00000218552;OTTHUMP00000218553;OTTHUMP00000218554;PARK 1;PARK 4;PARK1;PARK4;Parkinson disease (autosomal dominant;Lewy body) 4;Parkinson disease familial 1;SNCA;Snca synuclein;alpha (non A4 component of amyloid precursor);SYN;Synuclein alpha;Synuclein alpha 140;Synuclein;alpha (non A4 component of amyloid precursor);SYUA抗体
|
Swissprot |
P37840,O55042,P37377
|
Calculated MW |
14kDa
|
Observed MW |
15-19kDa
|
Cellular Localization |
Cytoplasm, cytosol. Membrane. Nucleus. Cell junction, synapse. Secreted. Membrane-bound in dopaminergic neurons.
|
Concentration |
0.92 mg/mL
|
Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
Buffer |
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
|
Purification Method |
Affinity purification
|
Research Areas |
Cancer; Neuroscience
|
Conjugation |
Unconjugated
|
Background |
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
|
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