- ￥580 - 2310
- Elabscience
- 湖北武汉
- E-AB-22205
- 2025年10月22日
- IHC-p
- Mouse
- Human;Mouse;Rat
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human;Mouse;Rat
- 保质期：
12个月
- 级别：
科研
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 宿主：
Mouse
- 应用范围：
IHC-p
- 抗体英文名：
STAT1 Monoclonal Antibody
- 抗体名：
STAT1 Monoclonal Antibody_货号:E-AB-22205_单克隆抗体
- 规格：
120μL/60μL/20μL
| 规格： | 120μL | 产品价格： | ￥2310.0 |
|---|---|---|---|
| 规格： | 60μL | 产品价格： | ￥1420.0 |
| 规格： | 20μL | 产品价格： | ￥580.0 |
STAT1 Monoclonal Antibody
| Verified Samples |
Verified Samples in IHC: Human breast carcinoma, Human colon carcinoma
|
| Dilution |
IHC 1:100-200
|
| Clonality |
Monoclonal
|
| Isotype |
IgG
|
| Immunogen |
Synthetic Peptide of STAT1
|
| Abbre |
STAT1 Mouse (5H7)
|
| Synonyms |
CANDF7, DKFZp686B04100, IMD31A, IMD31B, IMD31C, ISGF 3, ISGF-3, OTTHUMP00000163552, OTTHUMP00000165046, OTTHUMP00000165047, OTTHUMP00000205845, Signal tr, Signal transducer and activator of transcription 1 91kD, Signal transducer and activator of transcription 1 91kDa
|
| Swissprot |
P42224
|
| Cellular Localization |
Cytoplasm. Nucleus. Translocated into the nucleus in response to IFN-gamma-induced tyrosine phosphorylation and dimerization.
|
| Concentration |
1 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4.
|
| Purification Method |
Protein A purification
|
| Research Areas |
Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
|
| Clone No. |
5H7
|
| Conjugation |
Unconjugated
|
| Background |
Signal transducer and activator of transcription that mediates signaling by interferons (IFNs). Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state.
|
STAT1 Monoclonal AntibodyElabscience®提供8000+经过实验验证的高品质一抗，主要包括： 流式抗体、 单抗、 多抗、 重组抗体、 内参/标签抗体、 乙酰化/磷酸化/甲基化抗体、 磁珠/凝胶偶连抗体、 病毒抗体等。
STAT1 Monoclonal AntibodyStore at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
STAT1 Monoclonal Antibody产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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