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- Elabscience
- E-AB-F1197C
- 湖北武汉
- 2025年10月11日
- ICFCM
- Rat
- Mouse
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- 技术资料
- 抗体名：
FITC Anti-Mouse IL-10 Antibody流式抗体[JES5-16E3]_货号:E-AB-F1197C
- 抗体英文名：
FITC Anti-Mouse IL-10 Antibody[JES5-16E3]_货号:E-AB-F1197C
- 应用范围：
ICFCM
- 宿主：
Rat
- 适应物种：
Mouse
- 保质期：
12个月
- 目录编号：
E-AB-F1197C
- 级别：
科研
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 标记物：
FITC
- 克隆性：
Monoclonal
- 保存条件：
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 形态：
液体
- 亚型：
Rat IgG2b, κ
- 规格：
100Tests/50Tests/100Tests×2
| 规格： | 100Tests | 产品价格： | ￥1740.0 |
|---|---|---|---|
| 规格： | 50Tests | 产品价格： | ￥1020.0 |
| 规格： | 100Tests×2 | 产品价格： | ￥2640.0 |
产品名称：FITC Anti-Mouse IL-10 Antibody[JES5-16E3]
货号：E-AB-F1197C
| Background |
L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production); and promotes mast cell proliferation in combination with IL-4.
|
| Alternate Names |
Interleukin-10;IL-10;Cytokine synthesis inhibitory factor;CSIF;
|
| Swissprot |
P18893
|
| Gene ID |
16153
|
| Clone No |
JES5-16E3
|
| Host |
Rat
|
| Reactivity |
Mouse
|
| Application |
ICFCM
|
| Isotype |
Rat IgG2b, κ
|
| Isotype Control |
FITC Rat IgG2b, κ Isotype Control[LTF-2]
|
| Conjugation |
FITC
|
| Conjugation Information |
FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
|
| Spectrum |
 |
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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文献和实验-
Activin A promoted the anti-tumor effect of ActRIIA high CD8+ T cells in mouse hepatoma
IF: 2.9Journal： Cancer Medicine (2024)DOI：10.1002/cam4.70147Reactivity：Mouse
suspension. 5) Label another sample tube for each fluorochrome-conjugated antibody you are using, and add 1 drop of AbC™ capture beads (Component A in the AbC™ Anti-Mouse Bead Kit) to each tube. 6) Add a pre-titrated
min。②荧光素的准备 根据欲标记的蛋白质总量，按每毫克免疫球蛋白加0．01mg荧光色素，用分析天平准确称取所需的异硫氰酸荧光素粉末。也可用下述公式计算出免疫球蛋白、荧光素的量，还可以算出需加缓冲液的量。a．蛋白溶液：含量Amg／m1；容积Bml。b．总蛋白量(AXB)＝Crag。c．C／20～C／10＝Dmg(如蛋白含量低于20mg／ml，用C／10；如高于20mg／ml，用C／20)。d．荧光素FITC的量：(1／50～2／100)XC＝Emg。e．巳0．5mol／L(pH9．5)碳酸盐缓冲
来瓶「红牛」继续干！唐力团队发现 IL-10 可激活终末耗竭 T 细胞，为增强肿瘤免疫治疗提供新思路
exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity 的研究成果。该研究发现，IL-10 通过上调线粒体丙酮酸载体依赖的氧化磷酸化，从而介导 T 细胞代谢重编程，进而恢复终末耗竭 T 细胞的活力，并增强癌症免疫治疗的反应。 图片来源：Nature Immunology研究内容IL-10 直接扩增终末耗竭的 CD8 + 细胞作者首先制备了重组的人 IL-10 和 IgG1 Fc 的融合蛋白（IL-10–Fc），该蛋白可以与小鼠 IL-10 受体
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