Purified Anti-Human CD16 Antib

CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

FcγRIII;Fc gamma receptor;Fc gamma receptor 3;

P08637;O75015;

941

3G8

Mouse

Human

FCM;Block

Mouse IgG1, κ

Purified Mouse IgG1, κ Isotype Control[MOPC-21]

Unconjugated

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.

This product can be stored at 2-8°C for 12 months. Do not freeze.

12个月

冰袋