Size:50ug Protein Name: BDNF Synonym: BDNF;Brain Derived Neurotrophic Factor; Abrineurin; BDNF precursor form Uniprot No.: P23560 Expression System:E. Coli Compound Identity: BDNF(e1)-his Full Length or Truncated:Full length Molecular Weight: 28.2kD Form: freeze-dried powder Storage: -80°C (as supplied) Stability: ≤6 months Purity: ≥90% estimated by SDS-PAGE Supplied in:1×PBS (pH 7.2)
Background
Neurotrophins function to regulate naturally occurring cell death of neurons duringdevelopment. The prototype neurotrophin is nerve growth factor (NGF), originally discovered inthe 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from,sympathetic ganglia. Three additional structurally homologous neurotrophic factors have beenidentified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) andneurotrophin-4 (NT-4) (also designated NT-5).