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文献和实验Hyperspectral Imaging of FRET-Based cGMP Probes
:365–70, 2008). The probes are comprised of known cGMP binding sites—e.g., from phosphodiesterase type 5 (PDE5) or protein kinase G (PKG)—attached to fluorescent proteins. Binding of cGMP triggers conformational changes that alter the emitted
Genomic Analysis of Transgenic Animals by the Polymerase Chain Reaction
Once transgenic animals have been made and founder animals identified, it is usually necessary to establish lines of animals carrying the transgene. Since the founder animal will be hemizygous with respect to the transgene, at most 50
Gene Therapy Vectors Harboring AFP Regulatory Sequences: Preparation of an Adenoviral Vector
A goal of cancer research is to develop therapies that can selectively kill tumor cells without adversely affecting normal cells. In the case of hepatocellular carcinoma (HCC), there is a possibility that this goal may be achieved
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