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文献和实验Peptide Aptamers for Small Molecule Drug Discovery
molecules that displace interactions between proteins and their cognate peptide aptamers. AptaScreen is a duplex yeast two-hybrid assay featuring two luciferase reporter genes. It can be performed in 96- or 384-well plates and can be fully automated.
High‐Throughput RT‐PCR for Small‐Molecule Screening Assays
Turbocapture cDNA kit (Qiagen, cat. no. 72271 for 384‐well, 72251 for 96‐well plates) Buffer TCL (Qiagen, cat. no. 1031586
Selecting, Acquiring, and Using Small Molecule Libraries for High‐Throughput Screening
of high?quality small molecule libraries for screening is an essential aspect of drug discovery and chemical biology programs. Screening libraries continue to evolve as researchers gain a greater appreciation of the suitability of small molecules
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