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文献和实验to utilize animal models of disease states, to test experimental therapeutics, and to understand the underlying pathophysiology of neurodegenerative disease, behavioral characterization of the model is essential. Deterioration of normal motor function
! For preparative rotors, be sure the rotor cover is in place and properly screwed down, where appropriate. NEVER use a rotor without its lid, when one is supplied - the screw actually holds the rotor to the motor shaft. Check that the centrifuge chamber is clean
of centrifugal force is known as ultracentrifugation. The design of the basic instruments, the rotors and the optical systems for measurement are too extensive to cover in this volume. For our purposes, we will concentrate on two types of rotor
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