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- 2025年12月05日
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Type II TRK inhibitor 2
MCE 国际站：Type II TRK inhibitor 2
产品活性：Type II TRK inhibitor 2 (compound 40l) 是选择性的 II 型 TRK 抑制剂，具有血浆稳定性和中等肝微粒体稳定性。Type II TRK inhibitor 2 显着抑制 Km-12、Ba/F3-TRKAG595R 和 Ba/F3-TRKAG667C 细胞增殖 (IC50: 4.1 nM，41.5 nM，1.4 nM)。Type II TRK inhibitor 2 可用于 NTRK 融合癌症的研究。
研究领域：Neuronal Signaling | Protein Tyrosine Kinase/RTK
作用靶点：Trk Receptor
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文献和实验Isolation and Culture of Alveolar Epithelial Type I and Type II Cells from Rat Lungs
The pulmonary alveolar epithelium, comprised of alveolar Type I (TI) and Type II (TII) cells, covers more than 99% of the internal surface area of the lungs. The study of isolated and cultured alveolar epithelial TI and TII cells has provided
Immunoassays for Collagenase-Mediated Cleavage of Type I and II Collagens
This chapter describes the production and characterization of antibodies raised against neoepitopes in collagenase-cleaved collagen. It also details the development, validation, and use of immunoassays using such antibodies to measure
The Detection of Antibodies to the Angiotensin II-Type 1 Receptor in Transplantation
The detection of auto-antibodies detection is a major aspect of patient’s immunomonitoring. Antibodies directed against the heart and kidney Angiotensin II type 1 receptor (AT1 R) play a major role in antibody mediated rejection after heart
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