- ￥10600 - 17500
- TargetMol
- 美国
- T61054
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Type II topoisomerase inhibitor 1
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2245691-60-3
- 规格：
50 mg/100 mg/25 mg
| 规格： | 50 mg | 产品价格： | ￥13800.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥17500.0 |
| 规格： | 25 mg | 产品价格： | ￥10600.0 |
Product Introduction
Bioactivity
英文名:Type II topoisomerase inhibitor 1
描述:Type II topoisomerase inhibitor 1 is able to be used in the antibacterial area. Type II topoisomerase inhibitor 1 is a potent and selective inhibitor of E. coli DNA gyrase with a IC50 value of 1.7 nM as well as forms hydrogen bonds with Asp73 residue. Type II topoisomerase inhibitor 1 inhibits topoisomerase IV activity with an IC50 value of 0.98 μM [1] [2].
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文献和实验Purification of the Bacteriophage T4 Type II DNA Topoisomerase
Bacteriophage T4 encodes a type II topoisomerase with properties more similar to those of the eukaryotic class of enzymes than to those of the bacterial DNA gyrase (1 ,2 ). Indeed, the discovery of the T4 topoisomerase provided
The Dynamics of DNA Topoisomerase II in Living Cells
Here, we describe methods to prepare a mammalian expression plasmid encoding EGFP fused to the amino-terminus of human DNA topoisomerase IIα (Topo IIα) for use in studying the dynamics of Topo IIα in living cells. In previous studies
Depletion and Mutation of Topoisomerase II in Animal Cells
Eukaryotic type II topoisomerases (Topo II) are implicated in a wide range of cellular processes. Cells in which Topo II protein has been specifically depleted or mutated provide powerful systems for analysing the normal in vivo functions
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