Phosphotyrosine 抗体 [PY20] (PE)

Phosphotyrosine 抗体 [PY20] (PE)，Phosphotyrosine Antibody [PY20] (PE)，Phosphotyrosine 抗体 [PY20] (PE),Phosphotyrosine Antibody [PY20] (PE)

产品名称：Phosphotyrosine 抗体 [PY20] (PE)-Phosphotyrosine Antibody [PY20] (PE)

产品货号：PSI-98-518-0.1mg

产品规格：0.1mg

背景资料：Protein tyrosine residues are phosphorylated as a result of intracellular protein kinase activation (e.g., via growth factors) during normal growth and development and in oncogenesis. The most abundant population of target proteins for tyrosine phosphorylation is cell surface glycoproteins. Antibodies to phosphotyrosine enable the detection, isolation, and characterization of proteins containing phosphotyrosine. The monoclonal antibody PY20 prevents internalization of activated receptors (e.g., EGFR) when microinjected into cells. The affinity of PY20 for phosphotyrosine is approximately 10-6 to 10-7 M. PY20 binding to phosphorylated tyrosines can be inhibited by free phosphotyrosine and phenylphosphate but not by phosphoserine, phosphothreonine, or free phosphate.

保存建议：Phosphotyrosine 抗体 [PY20] (PE)-Phosphotyrosine Antibody [PY20] (PE)Store vial at 2-8℃

应用类型：E

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