CD5 抗体 [53-7.3] (PE),CD5 Antibody [53-7.3] (PE),CD5 抗体 [53-7.3] (PE),CD5 Antibody [53-7.3] (PE)
产品名称:CD5 抗体 [53-7.3] (PE)-CD5 Antibody [53-7.3] (PE)
产品货号:PSI-98-611-0.1mg
产品规格:0.1mg
背景资料:CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.
保存建议:CD5 抗体 [53-7.3] (PE)-CD5 Antibody [53-7.3] (PE)Store vial at 2-8℃
应用类型:E, IHC-P, IHC-Fr, ICC, Flow, IP, Neut, Multiplex
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