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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Mouse CTL clone V4
- 保存条件:
Store vial at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
大鼠
- 应用范围:
E, WB, IHC-P, IHC-Fr, Flow, Neut
- 抗体英文名:
CD4 Antibody [GK1.5] (APC-Cy5.5)
- 抗体名:
CD4 Antibody [GK1.5] (APC-Cy5.5)
- 规格:
0.1mg
CD4 抗体 [GK1.5] (APC-Cy5.5),CD4 Antibody [GK1.5] (APC-Cy5.5),CD4 抗体 [GK1.5] (APC-Cy5.5),CD4 Antibody [GK1.5] (APC-Cy5.5)
产品名称:CD4 抗体 [GK1.5] (APC-Cy5.5)-CD4 Antibody [GK1.5] (APC-Cy5.5)
产品货号:PSI-98-594-0.1mg
产品规格:0.1mg
背景资料:CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.
保存建议:CD4 抗体 [GK1.5] (APC-Cy5.5)-CD4 Antibody [GK1.5] (APC-Cy5.5)Store vial at 2-8℃
应用类型:E, WB, IHC-P, IHC-Fr, Flow, Neut
点击:CD4 抗体 [GK1.5] (APC-Cy5.5)-CD4 Antibody [GK1.5] (APC-Cy5.5)查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验流式课堂 | 易被忽略的 CD4、CD8 共表达细胞——胸腺淋巴细胞
做过流式实验的同学,对 CD4、CD8 这两个指标都不会陌生。检测 CD4+ T 细胞和 CD8+ T 细胞分型,是流式中最常见的实验之一。 通常,我们会先检测 CD3,来圈总T淋巴细胞,再分别用 CD4 抗体和 CD8 抗体,来区分 CD4+ T 淋巴细胞(辅助或调节性T细胞)和 CD8+ T 淋巴细胞(细胞毒性 T 细胞)。 新生小鼠脾脏细胞 上图为新生小鼠脾脏细胞进行的 CD3-PE、CD4-FITC、CD8-APC 三色流式实验结果。从图中可以看出,在新生小鼠脾脏中,绝大
: Type 1 (used for FITC, Cy5, and the initial preparation of the Cy5 and Cy7 tandem dyes); Type 2 (used for Biotin and Cascade Blue); Type 3 (used for conjugation of PE, APC, TR-BSA, and their derivatives); and Type 4 (used for the initial preparation
dyes. The conjugations fall into four basic protocols: Type 1 (used for FITC, Cy5, and the initial preparation of the Cy5 and Cy7 tandem dyes); Type 2 (used for Biotin and Cascade Blue); Type 3 (used for conjugation of PE, APC, TR-BSA
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