Integrin beta3 (phospho Tyr785

Integrin beta3 (phospho Tyr785) 抗体，Integrin beta3 (phospho Tyr785) Antibody，Integrin beta3 (phospho Tyr785) 抗体,Integrin beta3 (phospho Tyr785) Antibody

产品名称：Integrin beta3 (phospho Tyr785) 抗体-Integrin beta3 (phospho Tyr785) Antibody

产品货号：PSI-79-490-0.1mg

产品规格：0.1mg

背景资料：Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

保存建议：Integrin beta3 (phospho Tyr785) 抗体-Integrin beta3 (phospho Tyr785) AntibodyStore antibody at -20℃ for up to one year

应用类型：WB

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