- ￥22
- ProSci
- 美国
- PSI-79-235-0.1mg
- 2025年07月10日
- WB, IHC, IF
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Shc1 (Phospho-Tyr427) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 427 (P-S-Y (p) -V-N derived from Human Shc1.
- 保存条件：
Store antibody at -20℃ for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
WB, IHC, IF
- 抗体英文名：
Shc1 (phospho Tyr427) Antibody
- 抗体名：
Shc1 (phospho Tyr427) Antibody
- 规格：
0.1mg
Shc1 (phospho Tyr427) 抗体，Shc1 (phospho Tyr427) Antibody，Shc1 (phospho Tyr427) 抗体,Shc1 (phospho Tyr427) Antibody
产品名称：Shc1 (phospho Tyr427) 抗体-Shc1 (phospho Tyr427) Antibody
产品货号：PSI-79-235-0.1mg
产品规格：0.1mg
背景资料：Signaling adapter that couples activated growth factor receptors to signaling pathway. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span
保存建议：Shc1 (phospho Tyr427) 抗体-Shc1 (phospho Tyr427) AntibodyStore antibody at -20℃ for up to one year
应用类型：WB, IHC, IF
点击：Shc1 (phospho Tyr427) 抗体-Shc1 (phospho Tyr427) Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验Using Phospho‐Motif Antibodies to Determine Kinase Substrates
comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available
Optimized Protocol to Make Phospho-Specific Antibodies that Work
, not simply its level of expression. In this review, we will discuss both the design of the phosphopeptide immunogen and immunization. The affinity purification of the phospho-specific antibody as well as the methods most suitable for characterizing
Absorption Control in Immunohistochemistry Using Phospho-Peptides Immobilized on Magnetic Beads
neutralization of phospho-specific antibodies with phospho-peptides immobilized on magnetic beads. This technique allows for sequestration of antibody–peptide complex from the incubation solution, minimizing the risk of formation of unblocked antibodies capable
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