PAK1 抗体 -PAK1 Antibody

PAK1 抗体 ，PAK1 Antibody ，PAK1 抗体 ,PAK1 Antibody

产品名称：PAK1 抗体 -PAK1 Antibody

产品货号：PSI-63-291-400ul

产品规格：400ul

背景资料：PAK1, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It is likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2. The protein interacts tightly with GTP-bound but not GDP-bound CDC42/P21 and RAC1. PAK1 binds to the caspase-cleaved p110 isoform of CDC2L1 and CDC2L2, p110C, but not the full-length proteins. It is a component of cytoplasmic complexes, which also contain PXN, ARHGEF6 and GIT1. The protein is autophosphorylated when activated by CDC42/p21. Structurally, the PAK1 contains 1 CRIB domain.

保存建议：PAK1 抗体 -PAK1 Antibody Store at 4℃ for three months and -20℃, stable for up to one year

应用类型：WB, IHC-P, IF

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