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- ProSci
- 美国
- PSI-79-162-0.1mg
- 2025年07月10日
- WB, IHC, IF
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Rb (Phospho-Ser795) antibody was raised against a peptide sequence around phosphorylation site of serine 795 (P-S-S (p) -P-L) derived from Human Rb.
- 保存条件：
Store antibody at -20℃ for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
WB, IHC, IF
- 抗体英文名：
Rb (phospho Ser795) Antibody
- 抗体名：
Rb (phospho Ser795) Antibody
- 规格：
0.1mg
Rb (phospho Ser795) 抗体，Rb (phospho Ser795) Antibody，Rb (phospho Ser795) 抗体,Rb (phospho Ser795) Antibody
产品名称：Rb (phospho Ser795) 抗体-Rb (phospho Ser795) Antibody
产品货号：PSI-79-162-0.1mg
产品规格：0.1mg
背景资料：Key regulator of entry into cell division that acts as a tumor suppressor. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Inhibits the intrinsic kinase activity of TAF1. In case of viral infections, interactions with SV40 large T antigen, HPV E7 protein or adenovirus E1A protein induce the disassembly of RB1-E2F1 complex thereby disrupting RB1's activity.
保存建议：Rb (phospho Ser795) 抗体-Rb (phospho Ser795) AntibodyStore antibody at -20℃ for up to one year
应用类型：WB, IHC, IF
点击：Rb (phospho Ser795) 抗体-Rb (phospho Ser795) Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验【求助】于NF-KB 激活，P65磷酸化位点是ser536还是ser276?
伽利略 ............................... chenlydd 两者都有,蛋白磷酸化水平与其功能密切相关：检测其磷酸化水平可用抗磷酸化位点抗体检测。www.cellsignal.com公司有相应抗体出售。 P65磷酸化位点: regulates apoptosis: S536‑p regulates cell growth: S536‑p regulates cell
Using Phospho‐Motif Antibodies to Determine Kinase Substrates
comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available
Generation and Application of Phospho-specific Antibodies for p53 and pRB
of phosphoproteins. We have improved methods for generation of phosphorylation site-specific antibodies and have successfully obtained antibodies for the analysis of most of the phosphorylation sites on p53 and RB proteins.
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