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- ProSci
- 美国
- PSI-76-277-0.1mg
- 2025年07月13日
- Flow
- 仓鼠
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
protected from prolonged exposure to light
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
仓鼠
- 应用范围：
Flow
- 抗体英文名：
CD3e Antibody [145-2C11] (APC)
- 抗体名：
CD3e Antibody [145-2C11] (APC)
- 规格：
0.1mg
CD3e 抗体 [145-2C11] (APC)，CD3e Antibody [145-2C11] (APC)，CD3e 抗体 [145-2C11] (APC),CD3e Antibody [145-2C11] (APC)
产品名称：CD3e 抗体 [145-2C11] (APC)-CD3e Antibody [145-2C11] (APC)
产品货号：PSI-76-277-0.1mg
产品规格：0.1mg
背景资料：The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa epsilon chain of the TCR complex. Together with the gamma and delta subunits of CD3, the epsilon subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the epsilon chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.
保存建议：CD3e 抗体 [145-2C11] (APC)-CD3e Antibody [145-2C11] (APC) protected from prolonged exposure to light
应用类型：Flow
点击：CD3e 抗体 [145-2C11] (APC)-CD3e Antibody [145-2C11] (APC)查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验抗体的概念 抗体（antibody, Ab），也叫免疫球蛋白（immunoglobulin, Ig），是血液和组织液中的一类糖蛋白，由B细胞接受抗原刺激后增殖分化成的浆细胞产生，能与相应抗原特异性地结合，是介导体液免疫的重要效应分子。1968年和1972年世界卫生组织和国际免疫学联合会的专门委员会先后决定，将具有抗体活性或化学结构与抗体相似的球蛋白统称为免疫球蛋白。后来研究证实，Ig和Ab在结构及功能上完全一致，因此可认为二者的概念等同。Ig可分为分泌型和跨模型，前者主要存在于血液和组织液中
a 5-10 µg/ml solution of anti-CD3e (145-2C11) in sterile PBS. Calculate the number of wells required for each experimental condition and consider triplicate samples for each condition. For example, to coat one-half plate (48 wells) 2.6 ml of antibody
T-Cell Activation Using mAb to CD3
splenic T-cells and human peripheral T cells stimulated via CD3. Critical parameters include cell density, antibody titer and activation kinetics. Materials 1X sterile PBS Anti-mouse CD3e, Clone 145-2C11 (Functional Grade, Cat. No. 16
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