This RGS14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the Central region of human RGS14.
保存条件:
Store at 4℃ for three months and -20℃, stable for up to one year
背景资料:This gene encodes a member of the regulator of G-proteinsignaling family. This protein contains one RGS domain, twoRaf-like Ras-binding domains (RBDs), and one GoLoco domain. Theprotein attenuates the signaling activity of G-proteins by binding,through its GoLoco domain, to specific types of activated,GTP-bound G alpha subunits. Acting as a GTPase activating protein(GAP), the protein increases the rate of conversion of the GTP toGDP. This hydrolysis allows the G alpha subunits to bind Gbeta/gamma subunit heterodimers, forming inactive G-proteinheterotrimers, thereby terminating the signal. Alternatetranscriptional splice variants of this gene have been observed buthave not been thoroughly characterized.
保存建议:RGS14 抗体-RGS14 AntibodyStore at 4℃ for three months and -20℃, stable for up to one year