Tryptophan Hydroxylase (phosph
o Ser19) 抗体-Tryptophan Hydroxylase (phospho Ser19) Antibody- ￥22
- ProSci
- 美国
- PSI-50-242-0.1mL
- 2025年07月08日
- WB
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser19 of rat tryptophan hydroxylase 2 (TPH2).
- 保存条件：
stored at -20℃ and is stable at -20℃ for at least 1 year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
WB
- 抗体英文名：
Tryptophan Hydroxylase (phospho Ser19) Antibody
- 抗体名：
Tryptophan Hydroxylase (phospho Ser19) Antibody
- 规格：
0.1mL
Tryptophan Hydroxylase (phospho Ser19) 抗体，Tryptophan Hydroxylase (phospho Ser19) Antibody，Tryptophan Hydroxylase (phospho Ser19) 抗体,Tryptophan Hydroxylase (phospho Ser19) Antibody
产品名称：Tryptophan Hydroxylase (phospho Ser19) 抗体-Tryptophan Hydroxylase (phospho Ser19) Antibody
产品货号：PSI-50-242-0.1mL
产品规格：0.1mL
背景资料：Tryptophan hydroxylase (TPH) catalyzes the 5-hydroxylation of tryptophan, which is the first step in the biosynthesis of indoleamines (serotonin and melatonin) (Martinez et al., 2001). In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis. Serotonin functions mainly as a neurotransmitter, whereas melatonin is the principal hormone secreted by the pineal gland. The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CaM K II) (Jiang et al., 2000; Johansen et al., 1996). CaM K II phosphorylates Ser19 which lies within the regulatory domain of TPH2 (McKinney et
保存建议：Tryptophan Hydroxylase (phospho Ser19) 抗体-Tryptophan Hydroxylase (phospho Ser19) Antibody stored at -20℃ and is stable at -20℃ for at least 1 year
应用类型：WB
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