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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser301 of rat Raf-1.
- 保存条件:
stored at -20℃ and is stable at -20℃ for at least 1 year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB
- 抗体英文名:
Raf-1 (phospho Ser301) Antibody
- 抗体名:
Raf-1 (phospho Ser301) Antibody
- 规格:
0.1mL
Raf-1 (phospho Ser301) 抗体,Raf-1 (phospho Ser301) Antibody,Raf-1 (phospho Ser301) 抗体,Raf-1 (phospho Ser301) Antibody
产品名称:Raf-1 (phospho Ser301) 抗体-Raf-1 (phospho Ser301) Antibody
产品货号:PSI-50-237-0.1mL
产品规格:0.1mL
背景资料:The Ras pathway is a critical signal transduction cascade involved in regulating cellular proliferation, differentiation, survival, and oncogenic transformation. Members of the Raf serine/threonine kinase family are key intermediates in this cascade, functioning to relay signals from activated Ras to the downstream protein kinases MEK and ERK (Marshall, 1996). Previous studies have shown that phosphorylation is required for Raf-1 activation (Dhillon and Kolch, 2002; Chong et al., 2003). Recent work has demonstrated that phosphorylation also regulates the downregulation of Raf (Dougherty et al., 2005) with two sites participating: Ser301 and Ser642.
保存建议:Raf-1 (phospho Ser301) 抗体-Raf-1 (phospho Ser301) Antibody stored at -20℃ and is stable at -20℃ for at least 1 year
应用类型:WB
点击:Raf-1 (phospho Ser301) 抗体-Raf-1 (phospho Ser301) Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验【求助】于NF-KB 激活,P65磷酸化位点是ser536还是ser276?
伽利略 ............................... chenlydd 两者都有,蛋白磷酸化水平与其功能密切相关:检测其磷酸化水平可用抗磷酸化位点抗体检测。www.cellsignal.com公司有相应抗体出售。 P65磷酸化位点: regulates apoptosis: S536‑p regulates cell growth: S536‑p regulates cell
Using Phospho‐Motif Antibodies to Determine Kinase Substrates
comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available
Determination of ERK Activity: Anti-phospho-ERK Antibodies and In Vitro Phosphorylation
including proliferation, differentiation, and survival. In most of these cases, the ERK cascade is activated downstream of the small GTPase Ras that, upon activation, recruits and activates the first tier in the cascade, which contains the Raf kinases
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