ANGPTL4 抗体 [Kairos4-397G]-ANGP

ANGPTL4 抗体 [Kairos4-397G]，ANGPTL4 Antibody [Kairos4-397G]，ANGPTL4 抗体 [Kairos4-397G],ANGPTL4 Antibody [Kairos4-397G]

产品名称：ANGPTL4 抗体 [Kairos4-397G]-ANGPTL4 Antibody [Kairos4-397G]

产品货号：PSI-36-049-100ug

产品规格：100ug

背景资料：ANGPTL4 mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 is a protein consisting of an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain (FLD). Both domains have distinct biological functions. The coiled-coil domain is responsible for the inhibitory effects on lipoprotein lipase (LPL) converting the active form of LPL into an inactive form, and the FLD domain mediates its antiangiogenic functions. The coiled coil and the FLD domains are separated by a short linker that can be cleaved after secretion. ANGPTL4 appears on the cell surface as the full-length form, where it can be released by heparin treatment. ANGPTL4 protein is then proteolytically cleaved by proprotein convertases (PCs), including furin, PC5/6, paired basic amino acid-cleaving enzyme 4, and PC7.

保存建议：ANGPTL4 抗体 [Kairos4-397G]-ANGPTL4 Antibody [Kairos4-397G]Stable for at least 1 year after receipt when stored at -20℃

应用类型：E, WB

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