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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Human recombinant protein was used as the immunogen for this VIM antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
Flow, IF, WB, IHC
- 抗体英文名:
VIM Antibody [SPM576]
- 抗体名:
VIM Antibody [SPM576]
- 规格:
100ug
VIM 抗体 [SPM576],VIM Antibody [SPM576],VIM 抗体 [SPM576],VIM Antibody [SPM576]
产品名称:VIM 抗体 [SPM576]-VIM Antibody [SPM576]
产品货号:PSI-34-182-100ug
产品规格:100ug
背景资料:This mAb reacts with a 58kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFPs) such as desmin, keratin, neurofilament, and glial fibrillary acid protein. Anti-vimentin alone is of limited value as a diagnostic tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.
保存建议:VIM 抗体 [SPM576]-VIM Antibody [SPM576]Aliquot and Store at 2-8℃
应用类型:Flow, IF, WB, IHC
点击:VIM 抗体 [SPM576]-VIM Antibody [SPM576]查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验Rapid Characterization of -Lactamases by Multiplex PCR
to detect genes that encode five families of CTX-M-type ESBLs (groups 1, 2, 8, 9, and 25), five families of metallo-carbapenemases (IMP, VIM, SPM, GIM, and SIM enzymes), and four families of OXA-carbapenemases (OXA-23-like, OXA-40-like, OXA-51-like, and OXA
类水解能力存在较大差异,一般根据分子结构分为A、B、C、D四大类,其中B类酶在其活性部位结合有锌离子,因此又称为金属β-内酰胺酶。其水解底物包括青霉素类、头孢菌素类和碳青霉烯类等,表现为产酶细菌对这些药物广泛耐药。金属β-内酰胺酶首先在铜绿假单胞菌、不动杆菌中发现。近年来,在肠杆科细菌,如大肠埃希菌、肺炎克雷伯菌等中也有发现。迄今为止已经确定的金属β-内酰胺酶除NDM-1外,还包括IMP、VIM、GIM、SIM、SPM等型别。 最早报道的产NDM-1细菌为肺炎克雷伯菌,于2008年在一位印度裔
- 内酰胺酶抑制剂抑制,随着这些金属酶的出现,耐亚胺培南PA 的比例在增加,其中以VIM-2 型占主导地位。 目前PA 中发现的MBLs 有IMP、VIM、SPM 和GIM 共4 种类型,耐药基因由染色体或质粒介导。耐药方式产生形式多样,例如耐药酶的水平传播。这是一种借助整合子的移动及基因盒的插入、切除方式实现的传播方式。另外,由于基因环境的不断变化,基因盒与整合子可以出现不断进化,从而使得耐药方式不断更新。综上所述,PA 的耐药机制复杂,耐药相关基因繁多,不同的药物存在着不同的耐药机制,同一
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