BRCA1 抗体 [BRCA1/1398]-BRCA1 An

BRCA1 抗体 [BRCA1/1398]，BRCA1 Antibody [BRCA1/1398]，BRCA1 抗体 [BRCA1/1398],BRCA1 Antibody [BRCA1/1398]

产品名称：BRCA1 抗体 [BRCA1/1398]-BRCA1 Antibody [BRCA1/1398]

产品货号：PSI-33-613-100ug

产品规格：100ug

背景资料：BRCA1 (Breast cancer type 1 susceptibility protein) is a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene.

保存建议：BRCA1 抗体 [BRCA1/1398]-BRCA1 Antibody [BRCA1/1398]Aliquot and Store at 2-8℃

应用类型：Flow, IF, IHC-P

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